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. 2020 Dec 5;9(24):e017876. doi: 10.1161/JAHA.120.017876

Figure 6. Publication bias assessment.

Figure 6

Funnel plots for cerebral hemorrhage (A), infarct size (B), and neurobehavioral score (C), showing the distribution of published study outcomes (black circles) and additional missing outcomes (gray circles) imputed by trim and fill. The vertical black lines represent the actual estimate, and the gray vertical lines represent the theoretical estimate, when publication bias does not exist. Egger regression for cerebral hemorrhage (D), infarct size (E), and neurobehavioral score (F), confirming potential evidence for publication bias. The short vertical lines represent the 95% CI. SMD indicates standardized mean difference.