Table 1.
Blood counts in Xpr1fl/fl, Xpr1fl/fl Pf4-Cre, and Xpr1fl/+ Pf4-Cre murine blood samples
| Xpr1fl/fl (n = 9) | Xpr1fl/fl Pf4-Cre (n = 11) | Xpr1fl/+ Pf4-Cre (n = 18) | P | |
|---|---|---|---|---|
| RBC (×106/μL) | 9.40 ± 1.17 | 9.73 ± 0.61 | 9.31 ± 0.93 | .43 |
| Hgb (g/dL) | 14.24 ± 1.69 | 14.61 ± 0.75 | 13.81 ± 1.09 | .53 |
| HCT (%) | 47.66 ± 7.03 | 49.33 ± 3.45 | 46.86 ± 5.36 | .50 |
| MCV (fL) | 50.55 ± 01.87 | 50.71 ± 1.70 | 50.30 ± 1.68 | .85 |
| MCH (pg) | 15.18 ± 0.49 | 15.04 ± 0.40 | 14.88 ± 0.47 | .48 |
| MCHC (g/dL) | 30.03 ± 1.32 | 29.67 ± 1.19 | 29.61 ± 0.47 | .53 |
| RDW-SD (fL) | 29.62 ± 2.22 | 29.10 ± 1.74 | 30.24 ± 1.89 | .55 |
| RDW-CV (%) | 22.76 ± 2.08 | 23.02 ± 1.19 | 23.07 ± 1.63 | .72 |
| RET (×103/μL) | 379.41 ± 111.22 | 386.60 ± 97.83 | 355.38 ± 82.14 | .88 |
| RET (%) | 4.01 ± 0.93 | 3.97 ± 0.97 | 3.82 ± 0.80 | .92 |
| PLT (×103/μL) | 607.67 ± 266.56 | 717.54 ± 347.24 | 757.17 ± 300.98 | .44 |
| PDW (fL) | 7.21 ± 0.80 | 7.20 ± 0.40 | 6.96 ± 0.86 | .97 |
| MPV (fL) | 6.36 ± 0.43 | 6.23 ± 0.38 | 6.05 ± 0.52 | .49 |
| P-LCR (%) | 5.03 ± 2.39 | 3.59 ± 1.11 | 3.55 ± 2.14 | .09 |
| PCT (%) | 0.37 ± 0.19 | 0.45 ± 0.22 | 0.46 ± 0.18 | .38 |
| WBC (×103/μL) | 6.22 ± 4.71 | 6.96 ± 3.53 | 6.73 ± 4.11 | .69 |
| NEUT (×103/μL) | 0.86 ± 0.90 | 1.18 ± 0.91 | 0.95 ± 1.02 | .44 |
| LYMPH (×103/μL) | 5.14 ± 3.96 | 5.56 ± 3.06 | 5.56 ± 3.25 | .79 |
| MONO (×103/μL) | 0.11 ± 0.13 | 0.12 ± 0.06 | 0.09 ± 0.05 | .80 |
| EO (×103/μL) | 0.11 ± 0.08 | 0.09 ± 0.08 | 0.12 ± 0.12 | .50 |
| BASO (×103/μL) | 0.00 ± 0.00 | 0.01 ± 0.01 | 0.00 ± 0.01 | N/A |
| NEUT (%) | 13.8 ± 10.1 | 17.0 ± 12.4 | 12.8 ± 7.0 | .54 |
| LYMPH (%) | 82.7 ± 11.0 | 79.9 ± 12.3 | 83.8 ± 7.4 | .60 |
| MONO (%) | 1.7 ± 0.9 | 2.0 ± 1.1 | 1.7 ± 1.4 | .54 |
| EO (%) | 1.87 ± 0.79 | 1.08 ± 0.61 | 1.69 ± 1.03 | .2 |
| BASO (%) | 0.01 ± 0.03 | 0.07 ± 0.10 | 0.07 ± 0.15 | N/A |
Data are expressed as the mean ± standard deviation. P values represent Xpr1fl/fl Pf4-Cre vs Xpr1fl/fl murine blood counts.
BASO, basophil; EO, eosinophil; HCT, hematocrit; Hgb, hemoglobin; LYMPH, lymphocyte; MCH, mean corpuscular hemoglobin, MCHC, mean corpuscular hemoglobin concentration; MCV, mean corpuscular volume; MPV, mean platelet volume; MONO, monocyte; N/A, not applicable, because the absolute number of events counted was too low to perform statistical analysis; NEUT, neutrophil; PCT, plateletcrit; PDW, platelet distribution width; P-LCR, platelet large-cell ratio; PLT, platelet; RBC, red blood cell; RDW-SD, red cell distribution width standard deviation; RDW-CV, red cell distribution coefficient of variation; RET, reticulocyte; WBC, white blood cell.