Table 3.
HR for the Association Between Changes in Pre–Diabetes Mellitus From 2006 to 2008 and the Incidence of Ischemic Stroke and Hemorrhagic Stroke
| Variable | Changes in Pre–Diabetes Mellitus | ||
|---|---|---|---|
| Progression to Diabetes Mellitus | Persistent Pre–Diabetes Mellitus | Normoglycemia | |
| Ischemic stroke | |||
| No. of cases | 121 | 266 | 227 |
| Incidence rate, per 1000 person‐years | 5.91 | 4.13 | 3.26 |
| Model 1 | Reference | 0.80 (0.64–1.00) | 0.65 (0.52–0.82) |
| Model 2 | Reference | 0.80 (0.64–0.99) | 0.65 (0.52–0.82) |
| Model 3 | Reference | 0.86 (0.68–1.07) | 0.72 (0.56–0.91) |
| Hemorrhagic stroke | |||
| No. of cases | 17 | 43 | 44 |
| Incidence rate, per 1000 person‐years | 0.81 | 0.66 | 0.63 |
| Model 1 | Reference | 0.90 (0.51–1.58) | 0.82 (0.47–1.46) |
| Model 2 | Reference | 0.90 (0.51–1.59) | 0.83 (0.47–1.47) |
| Model 3 | Reference | 0.98 (0.55–1.76) | 0.96 (0.53–1.76) |
Data are given as HR (95% CI), unless otherwise indicated. Model 1, adjusted for age and sex. Model 2, adjusted for age, sex, income, education, current smoking status, current drinking status, and physical activity. Model 3, adjusted for variables in model 2 plus hypertension, dyslipidemia, fasting plasma glucose, body mass index, estimated glomerular filtration rate, and hs‐CRP (high‐sensitivity C‐reactive protein). HR indicates hazard ratio.