Table 1.
Baseline Characteristics at Implantation in the Follow‐Up Population and Study Subgroups
| Characteristic | Follow‐Up Population | ICM | DCM | VHD | HCM | ARVC | LQTS | BS | ACHD |
|---|---|---|---|---|---|---|---|---|---|
| No. (%) | 4296 (100) | 2150 (50) | 1166 (27.1) | 119 (2.8) | 294 (6.8) | 71 (1.7) | 43 (1) | 143 (3.3) | 60 (1.4) |
| Age, mean±SD, y | 61.9±12.9 | 65.6±10.1 | 62.1±12.1 | 63.5±12.6 | 52.6±15.1 | 47.4±11.9 | 51.1±18.5 | 50.3±12.6 | 45.6±14.2 |
| Sex (men) | 3527 (82.1) | 1938 (90.2) | 878 (75.3) | 90 (75.6) | 216 (73.5%) | 51 (71.8) | 12 (27.9) | 120 (83.9) | 34 (56.7) |
| Hypertension | 2275 (54.4) | 1358 (65) | 598 (52.4) | 60 (52.2) | 109 (37.7) | 14 (20.6) | 11 (25.6) | 24 (16.8) | 11 (18.3) |
| Diabetes mellitus | 1178 (28.3) | 758 (36.4) | 312 (27.5) | 24 (21.1) | 30 (10.3) | 0 (0) | 3 (2.3) | 9 (5.6) | 4 (6.7) |
| Hypercholesterolemia | 2040 (52.5) | 1291 (65.8) | 462 (43.8) | 40 (39.6) | 111 (41.6) | 16 (24.6) | 6 (12.5) | 33 (25.6) | 13 (22) |
| Smoking status | 1415 (37.7) | 852 (45.2) | 345 (33.8) | 21 (21.4) | 69 (26) | 10 (15.9) | 3 (7.7) | 40 (32.5) | 10 (16.9) |
| History of atrial fibrillation | 1235 (29.4) | 608 (29) | 401 (35.1) | 62 (53) | 89 (30.5) | 3 (4.3) | 7 (16.3) | 5 (3.5) | 13 (21.7) |
| Previous stroke | 252 (6.8) | 145 (7.9) | 60 (5.9) | 9 (9) | 17 (6.1) | 1 (1.7) | 3 (7.9) | 2 (1.6) | 3 (5.1) |
| Chronic kidney disease | 633 (15.3) | 380 (18.4) | 183 (16.3) | 17 (14.8) | 19 (6.6) | 3 (4.3) | 3 (7) | 4 (2.8) | 4 (6.7) |
| Family history of SCD | 356 (8.7) | 48 (2.4) | 93 (8.3) | 3 (2.7) | 104 (36.4) | 15 (22.1) | 10 (23.8) | 44 (31.9) | 14 (23.7) |
| LV ejection fraction, % | |||||||||
| ≤35 | 2841 (66.4) | 1633 (76.3) | 996 (85.6) | 64 (53.8) | 34 (11.6) | 11 (15.5) | 1 (2.3) | 1 (0.7) | 25 (41.7) |
| 36–50 | 631 (14.7) | 379 (17.7) | 131 (11.3) | 27 (22.7) | 35 (11.9) | 11 (15.5) | 5 (11.6) | 5 (3.5) | 9 (15) |
| >50 | 806 (18.9) | 128 (5.9) | 36 (3.1) | 28 (23.5) | 224 (76.5) | 49 (69) | 37 (86) | 137 (95.8) | 26 (43.3) |
| QRS width, ms | |||||||||
| <120 | 2202 (52.4) | 1154 (53.7) | 389 (34) | 42 (35.9) | 196 (68.3) | 65 (91.5) | 35 (81.4) | 127 (90.1) | 23 (40.4) |
| 120–150 | 877 (20.9) | 479 (22.3) | 249 (21.7) | 32 (27.4) | 48 (16.7) | 5 (7) | 5 (11.6) | 11 (7.8) | 9 (15.8) |
| >150 | 1119 (26.7) | 466 (21.7) | 507 (44.3) | 43 (36.8) | 43 (15) | 1 (1.4) | 3 (7) | 3 (2.1) | 25 (43.9) |
| Previous heart failure | 2973 (69.8) | 1564 (73.1) | 986 (85.4) | 89 (75.4) | 133 (45.2) | 26 (36.6) | 11 (25.6) | 23 (16.1) | 40 (66.7) |
| Type of device | |||||||||
| VR | 2027 (47.2) | 1107 (51.5) | 356 (30.5) | 46 (38.7) | 137 (46.6) | 48 (67.6) | 16 (37.2) | 133 (93) | 23 (38.3) |
| DR | 972 (22.6) | 511 (23.8) | 168 (14.4) | 20 (16.8) | 142 (48.3) | 23 (32.4) | 26 (60.5) | 10 (7) | 21 (35) |
| CRT‐D | 1297 (30.2) | 532 (24.7) | 642 (55.1) | 53 (44.5) | 15 (5.1) | 0 (0) | 1 (2.3) | 0 (0) | 16 (26.7) |
| Primary prevention | 2758 (64.2) | 1342 (62.4) | 899 (77.1) | 53 (44.5) | 228 (77.6) | 22 (31) | 4 (9.3) | 110 (76.9) | 37 (61.7) |
Data are given as number (percentage) unless otherwise noted. ACHD indicates adult congenital heart disease; ARVC, arrhythmogenic right ventricular cardiomyopathy; BS, Brugada syndrome; CRT‐D, cardiac resynchronization therapy‐defibrillator; DCM, dilated cardiomyopathy; HCM, hypertrophic cardiomyopathy; ICM, ischemic cardiomyopathy; LQTS, long‐QT syndrome; LV, left ventricular; SCD, sudden cardiac death; and VHD, valvular heart disease.