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. 2020 Dec 17;10(1):e016696. doi: 10.1161/JAHA.120.016696

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© 2020 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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(A) Bars represent hind limb muscle perfusion measured as mean±SD uptake of ²⁰¹Tl (percentage injected dose [%ID]) for diabetic pigs treated with IgG (n=5) and anti–receptor for advanced glycation end products antibody (CR‐3) (n=6) at day 1 (dark gray bars) and day 28 (light gray bars). (B) Individual values for gastrocnemius (Gastroc) muscle perfusion at day 1 and day 28 for IgG treated pigs (blue) and CR‐3 treated pigs (orange). (C) Each bar represents change in Gastroc muscle perfusion as mean±SD between days 1 and 28 for IgG treated pigs (blue bar) and CR‐3 treated pigs (orange bar). Biceps fem indicates biceps femoris; and Semitendin, semitendinosus.