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. 2021 Mar 12;20:62. doi: 10.1186/s12933-021-01255-0

Table 1.

Comparison of descriptive data between young people with type 1 diabetes mellitus and apparently healthy peers without diabetes

T1DM (n = 48) Peers without diabetes (n = 19)
Mean SD Mean SD p Adjusted p
Sex (male/ female) (%) 37.5/62.5 42.1/57.9 0.129
Pubertal stage (n) 0.543
Stage 1 (Not started) 18 7
Stage 2 (Barely started) 8 1
Stage 3 (Definitely underway) 12 6
Stage 4 (Seems completed) 5 1
Stage 5 (Completed) 5 4
Ages (y) 14.02 2.89 13.58 3.46 0.601
Body mass (kg) 49.48 12.56 52.34 15.45 0.452
Height (m) 1.60 0.13 1.59 0.13 0.772
BMI (kg∙m−2) 18.97 3.10 20.38 3.32 0.119
BMI z-score − 0.27 1.16 0.50 1.01 0.018*
Body fat (%) 29.28 9.54 28.42 6.61 0.765 0.084
Waist circumference (cm) 67.63 7.96 73.65 8.22 0.055 0.151
Systolic blood pressure (mmHg) 106.07 16.72 107.07 15.45 0.837 0.778
Diastolic blood pressure (mmHg) 65.24 11.65 65.75 9.88 0.878 0.821
Total cholesterol (mmol∙L−1) 4.03 0.81 3.14 0.67 0.001* 0.001
HDL-C (mmol∙L−1) 1.48 0.28 1.29 0.42 0.078 0.184
LDL-C (mmol∙L−1) 2.31 0.72 1.74 0.38 0.005* 0.008
Triglycerides (mmol∙L−1) 0.89 0.31 0.60 0.40 0.012* 0.007
Estimated VO2max (mL∙kg−1∙min−1) 35.48 8.72 44.43 8.29 0.003* 0.003
METs (kcal∙h−1∙kg−1)‡ 2.09 0.41 2.41 0.60 0.066 0.075
Physical activity counts (CPM)‡ 346.87 101.97 451.01 133.52 0.004* 0.033
Light physical activity (min∙day−1)‡ 335.93 120.16 449.33 89.55 0.002* 0.003
Percentage of time spent in Sedentary behaviour (%)‡ 36.34 11.04 28.86 12.56 0.04* 0.095

Data are presented as means and standard deviation (SD)

T1DM type 1 diabetes mellitus, n number, y year, BMI body mass index, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol, VO2max maximal aerobic power, METs metabolic equivalents, CPM counts-per-minute, adjusted p ANCOVA adjusted for BMI z-score

*Statistically significant difference (p < 0.05) between T1DM and apparently healthy peers without diabetes

‡Sixteen of 19 apparently healthy participants not living with diabetes and 40 of 48 participants with T1DM had valid physical activity data