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. 2021 Mar 12;20:24. doi: 10.1186/s12940-021-00709-y

Table 1.

Maternal and child characteristics according to median (M) and 25–75 percentiles (25–75%) BPA concentrations in maternal urine; and percentage of children with an ADHD- or ASD- score above the 75th percentile at 2 or 5 years of age

Maternal and child characteristics N (%) BPA ng/mL
M (25–75%)
ASD-score > 75%
2 years
Percent
ASD-score > 75%
5 years
Percent
ADHD-score > 75%
5 years
Percent
658 (100) 1.2 (0.5–2.6)
Parity
 Nulliparous 371 (56) 1.37 (0.47–2.88) 32 42 29
 Multiparous 287 (44) 1.20 (0.49–2.26) 18 24 22
P-valuea 0.07 < 0.001* < 0.001* 0.08
Pre-pregnancy BMI (kg/m2)
  > 18.5- < 25 412 (62) 1.03 (0.30–2.32) 27 32 24
 25–30 169 (26) 1.82 (0.90–2.77) 24 33 28
  > 30 77 (12) 1.17 (0.55–2.97) 24 49 33
P-valuea 0.002* 0.65 0.06 0.35
Smoking
 No 639 (97) 1.23 (0.47–2.54) 25 32 25
 Yes 19 (3) 1.21 (0.63–2.68) 37 73 33
P-valuea 0.19 0.29 0.001* 0.49
Education b
 high school or less 177 (27) 1.53 (0.55–2.66) 32 54 39
 high school + 1–4 years 336 (53) 1.20 (0.49–2.73) 25 29 22
 high school + > 4 years 131 (20) 1.35 (0.33–2.24) 18 21 18
P-valuea 0.34 0.04* < 0.001* < 0.001*
Age
  < 25 61 (9) 1.08 (0.39–3.34) 40 35 44
 25–34 438 (67) 1.23 (0.47–2.49) 26 35 25
  > 34 159 (24) 1.28 (0.55–2.52) 19 30 21
P-valuea 0.82 0.006* 0.06 0.03*
Psychiatric predisposition
 None 565 (86) 1.27 (0.50–2.52) 24 33 24
 Predisposition from parents 93 (14) 1.14 (0.38–2.97) 36 42 33
P-valuea 0.88 0.01* 0.16 0.14
Birth weight (gram)
  ≤ 3560 332 (51) 1.24 (0.44–2.89) 27 42 27
  > 3560 326 (49) 1.23 (0.52–2.38) 25 26 24
P-valuea 0.13 0.52 < 0.001* 0.5
Exclusive breastfeeding (weeks)c
 0 101 (16) 1.96 (0.79–3.72) 23 45 36
 1–12 256 (42) 1.20 (0.47–2.38) 25 34 31
  > 12 259 (42) 1.24 (0.41–2.42) 27 32 18
P-valuea 0.22 0.65 0.18 0.005*
Gestation
  < 37 + 0 24 (4) 0.54 (0.00–2.73) 42 62 31
  > 37 + 0 634 (96) 1.23 (0.49–2.54) 25 33 26
P-valuea 0.84 0.07 0.03* 0.67

aP-value < 0.05 with Kruskal wallis test (BPA) or Chi2 test (Autistic- or ADHD symptoms)

b 4 observations missing

c42 observations missing