Figure 2: The type VI CRISPR system elicits collateral RNA cleavage in the native host.
A. Liquid growth assay of the indicated strains illustrating CRISPR-dependent growth defects in the presence of target with or without target selection. Error bars represent standard error of the mean from four biological replicates. B. Northern blot analysis of target (cat) and nontarget (5S rRNA) transcripts in the indicated strains.