Table 2. Structure predictions for the LRRC9 ART-like domain.

Structure and distant sequence similarity predictions for human LRRC9 ART-like region (residues 389-628) obtained using different bioinformatics tools. For each method, only the first hit shown.

Bioinformatic tool for structure prediction	Top hit: PDB code, name	Statistical significance for top hit	Region of query aligned to the hit	Sequence identity
FFAS03	4DVI Tankyrase 1 with IWR2	Z-score =-12.500	427-625	20%
HHpred	5LX6, Human PARP10 (ARTD10), catalytic fragment in complex with PARP inhibitor Veliparib [Homo sapiens ]	E-value =6.2e−23	392-624	15%
Phyre2	3HKV, Human poly(ADP-ribose) polymerase 10, catalytic fragment in complex with an inhibitor 3-aminobenzamide; chain A	Confidence= 100%	395-624	16%