Table 3.
Baseline Characteristics of the Patients According to the Subcategorized Groups of HT in Total Population
| Variables | Non-HT (n=285) | HI (n=143) | PH (n=123) | P-value |
|---|---|---|---|---|
| Demographic parameters | ||||
| Age (years) | 71.0 (17.0) | 72.0 (17.0) | 71.0 (19.0) | 0.730 |
| Male, n (%) | 193 (67.7%) | 98 (68.5%) | 84 (68.3%) | 0.984 |
| BMI (kg/m 2) | 23.0 (4.0) | 23.0 (3.3) | 22.9 (5.5) | 0.952 |
| Vascular risk factors | ||||
| History of stroke, n (%) | 31 (11.0%) | 24 (16.8%) | 14 (11.4%) | 0.208 |
| History of atrial fibrillation, n (%) | 29 (10.3%) | 46 (32.2%) | 58 (47.2%) | 0.000* |
| History of hypertension, n (%) | 197 (69.6%) | 97 (67.8%) | 71 (57.7%) | 0.061 |
| Diabetes, n (%) | 107 (37.8%) | 42 (29.4%) | 38 (30.9%) | 0.156 |
| History of dyslipidemia, n (%) | 17 (6.0%) | 14 (9.8%) | 5 (4.1%) | 0.151 |
| Current smoking, n (%) | 86 (30.2%) | 46 (32.6%) | 38 (31.4%) | 0.873 |
| Current drinking, n (%) | 71 (25.0%) | 44 (31.2%) | 34 (28.1%) | 0.391 |
| Biochemistry and vital signs on admission | ||||
| Baseline SBP (mmHg) | 157.0 (28.0) | 150.0 (28.0) | 145.0 (31.0) | 0.000* |
| Baseline DBP (mmHg) | 81.0 (19.0) | 82.0 (15.0) | 81.0 (17.0) | 0.773 |
| White cells counts (×109/L) | 6.6 (2.2) | 7.5 (3.9) | 8.6 (3.4) | 0.000* |
| Platelets (×109/L) | 205.0 (61.5) | 195.0 (75.0) | 177.0 (90.0) | 0.004 |
| Fibrinogen (g/L) | 3.3 (1.2) | 3.9 (1.5) | 3.8 (1.9) | 0.000* |
| Creatinine (μmol/L) | 72.0 (25.0) | 65.0 (21.0) | 70.0 (23.0) | 0.006 |
| Glucose levels (mmol/L) | 5.1 (1.9) | 5.8 (1.9) | 5.6 (2.5) | 0.004 |
| HbA1c (%) | 6.0 (1.7) | 6.0 (1.5) | 6.0 (1.3) | 0.464 |
| Total cholesterol (mmol/L) | 1.7 (2.1) | 4.2 (1.6) | 4.5 (1.3) | 0.000* |
| SHR | 0.87 (0.17) | 0.93 (0.28) | 1.00 (0.38) | 0.000* |
| NIHSS on admission, median (IQR) | 3.0 (4.0) | 7.5 (9.0) | 11.0 (8.0) | 0.000* |
| Stroke mechanisms | 0.000* | |||
| Atherosclerotic, n (%) | 214 (84.9%) | 107 (78.1%) | 64 (52.5%) | |
| Cardioembolic, n (%) | 20 (7.9%) | 28 (20.4%) | 56 (45.9%) | |
| Lacunar, n (%) | 3 (1.2%) | 1 (0.7%) | 0 (0.0%) | |
| Other causes, n (%) | 15 (6.0%) | 1 (0.7%) | 2 (1.6%) | |
| Initial treatment in hospital | ||||
| Antiplatelets, n (%) | 256 (91.1%) | 81 (56.6%) | 67 (54.5%) | 0.000* |
| Anticoagulants, n (%) | 28 (9.9%) | 38 (26.6%) | 45 (36.6%) | 0.000* |
| Lipid-lowering agents, n (%) | 261 (95.3%) | 125 (88.7%) | 103 (84.4%) | 0.001 |
Note: *P < 0.001.
Abbreviations: HT, hemorrhagic transformation; HI, hemorrhagic infarct; PH, parenchymal hematoma; BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institutes of Health Stroke Scale; SHR, stress hyperglycemia ratio.