Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 9;15:1075–1089. doi: 10.2147/DDDT.S275228

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2021 Bi et al.

This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).

PMC Copyright notice

PDGF induced ASM cells proliferation by activating AKT/mTOR pathway. (A–C) ASM cells were treated with PDGF (10ng/mL) for 1h, 5h, and 12h. The expression levels of p-AKT and p-mTOR were analyzed by Western blotting. The relative protein levels of P-AKT and P-mTOR were calculated by Image J, respectively and expressed as mean ± SD (n=3) of each group. * P < 0.05 and ** P < 0.01 vs control group. (D) ASM cells were treated with PDGF (10ng/mL) and LY294002 (10 μM), Rapamycin (500 nM) for 5h, respectively. Cell proliferation was detected by CCK-8. The data were expressed as mean ± SD (n=8) of each group, ** P<0.01 vs PDGF group, ^# P<0.01vs control group.