The presence of rare pathogenic SCN5A variants is associated with more severe phenotypes in Brugada syndrome patients, which may be at least partly explained by greater epicardial arrhythmogenic substrates in these patients.
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.