Table 6.
Summary of individual case reports of patients with post-infectious encephalitis and tics
Study | Country | Age | Sex | Aetiology of encephalitis | Tics | Other neuropsychiatric symptoms | Additional findings | Main limitations |
---|---|---|---|---|---|---|---|---|
Northam and Singer [30] | USA | 6 | F | Herpes simplex encephalitis | Eye blinking, grimacing, head twitching; complex motor and phonic tics (2 weeks after recovery) | Malaise, headache, seizures, nausea, and vomiting | Tics improved with antidopaminergic medication | Diagnosis of encephalitis lacking detail |
Dale et al. [31] | Australia | 4 | M | Varicella zoster encephalitis | Chronic motor tics affecting face and neck (2 months after onset) | Alterations of consciousness and tremor | Neuroimaging abnormalities (basal ganglia) | Link between neuroimaging abnormalities and tics lacking detail |
Sabuncuoğlu and Berkem [32] | Turkey | 9 | M | Mumps—meningoencephalitis | Eye blinking, finger flexing, throat clearing (2 months after recovery) | N/A | Tics improved with antidopaminergic medication | Link between mumps and tics lacking detail |
Molina and Feteke [33] | USA | 59 | F | Creutzfeldt-Jakob disease | Grunting and barking (5 months after onset) | Involuntary movements, akinetic mutism, catatonia, personality change | Patient was mute except for phonic tics | Limited generalisability of findings |
Dey and Bhattacharya [34] | India | 10 | M | Measles—subacute sclerosing panencephalitis | Insidious onset complex shoulder and facial tics | Ataxia and myoclonus | Tics as presenting symptoms | Limited generalisability of findings |
Anandatia et al. [35] | Philippines | 28 | F | Toxoplasma encephalitis secondary to human immunodeficiency virus | Motor/facial tics | Hemichorea and alterations of consciousness | N/A | Limited generalisability of findings |