Table 3.
Treatment tolerance.
| 65–69 Years n = 82 |
70–74 Years n = 72 |
75–70 Years n = 48 |
>80 Years n = 39 |
Total n = 241 |
p-Value | |
|---|---|---|---|---|---|---|
| % | % | % | % | % | ||
| Dose modification at baseline | 9.8 | 12.5 | 6.3 | 17.5 | 11.6 | 0.365 |
| Dose modification during chemotherapy | 29.3 | 30.6 | 52.1 | 37.5 | 35.5 | 0.193 |
| Completed 6 cycles of chemotherapy | 86.6 | 86.1 | 77.1 | 65.0 | 82.2 | 0.034 |
| ≥ G2 Haematological toxicity | 29.3 | 19.4 | 33.3 | 30.0 | 27.3 | 0.554 |
| ≥ G3 Non-haematological toxicity | 13.4 | 19.4 | 27.1 | 32.5 | 21.1 | 0.082 |
| Febrile neutropenia | 4.9 | 2.8 | 2.1 | 0.00 | 2.9 | 0.540 |
| Hospital admission during chemotherapy | 20.7 | 34.7 | 25.0 | 37.5 | 28.5 | 0.135 |
| Death within 30 days of chemotherapy | 1.2 | 0.00 | 4.2 | 0.00 | 1.2 | 0.184 |