Table 4.
Univariate and multivariate analysis of factors associated with poorer overall survival.
| Univariate | Multivariate | |||||||
|---|---|---|---|---|---|---|---|---|
| n | HR | 95% CI | p | HR | 95% CI | p | ||
| Age Cohort | 65–69 | 91 | - | - | - | - | - | - |
| 70–74 | 79 | 1.40 | (0.96–2.05) | 0.081 | 0.95 | (0.60–1.52) | 0.833 | |
| 75–79 | 53 | 1.07 | (0.68–1.68) | 0.772 | 0.79 | (0.44–1.43) | 0.441 | |
| >80 | 57 | 2.20 | (1.47–3.27) | 0.000 | 1.76 | (1.03–3.02) | 0.04 | |
| FIGO Stage | 1 | 37 | - | - | - | |||
| 2 | 28 | 1.30 | (0.55–3.07) | 0.553 | 7.91 | (0.98–63.61) | 0.052 | |
| 3 | 158 | 3.69 | (1.98–6.89) | 0.000 | 12.99 | (1.77–95.20) | 0.012 | |
| 4 | 55 | 6.00 | (3.08–11.68) | 0.000 | 16.16 | (2.11–123.61) | 0.007 | |
| ECOG PS | 0 | 56 | - | - | - | |||
| 1 | 122 | 1.86 | (1.18–2.93) | 0.007 | 2.14 | (1.21–3.79) | 0.009 | |
| 2 | 55 | 4.02 | (2.47–6.53) | 0.000 | 2.53 | (1.20–5.35) | 0.015 | |
| 3 | 26 | 7.36 | (4.13–13.13) | 0.000 | 3.51 | (1.37–8.99) | 0.009 | |
| Cardiovascular disease | 77 | 1.38 | (1.01–1.90) | 0.043 | 0.99 | (0.62–1.57) | 0.95 | |
| Taking 3 or more medications | 111 | 0.07 | (0.01–0.55) | 0.011 | 1.12 | (0.72–1.74) | 0.62 | |
| Osteoarthritis | 16 | 1.70 | (0.96–3.01) | 0.070 | 1.62 | (0.76–3.44) | 0.209 | |
| Reduced activities of daily living | 70 | 2.89 | (2.10–3.98) | 0.000 | 1.53 | (0.90–2.62) | 0.118 | |
| History of depression | 11 | 1.86 | (0.95–3.65) | 0.071 | 1.89 | (0.83–4.30) | 0.128 | |
| History of weight loss | 66 | 1.51 | (1.09–2.11) | 0.015 | 0.93 | (0.59–1.47) | 0.754 | |
| Albumin <35 g/L | 114 | 2.09 | (1.56–2.81) | 0.000 | 1.52 | (0.97–2.38) | 0.065 | |
| Haemoglobin <120 g/L | 141 | 1.28 | (0.9601.72) | 0.093 | 0.80 | (0.53–1.23) | 0.311 | |
| GFR <60 mL/min | 104 | 1.33 | (0.98–1.79) | 0.064 | 1.11 | (0.74–1.68) | 0.607 | |