ALT |
Alternative Lengthening of Telomeres |
Pol |
DNA Polymerase |
POT1/TTP1 |
Protection of Telomeres protein 1 |
HR |
Homologous Recombination |
RP-A |
Replication Protein A |
ECRTs |
Extra-Chromosomal Telomeric Repeats |
DSBs |
Double Strand Breaks |
aNHEJ |
Alternative Microhomology-Mediated Non-Homologous End Joining Pathway |
PARP-1 |
Poly (ADP-Ribose) Polymerase |
BIR |
Break Induced Replication |
TLS |
Translesion Synthesis |
MMST |
Microhomology Mediated Strand Transfer |
HU |
Hydroxyurea |
PML |
ALT-associated promyelocytic leukemia |
TERRA |
Telomeric Repeats Containing RNA |
TIFs |
telomere dysfunction-induced foci |