Table 1.
The inhibitory concentration (IC50) value of DMCH on colon cancer cell lines (SW620 and HT29) after 24, 48, and 72 h of treatment. Cytotoxicity effects of DMCH on colon cancer cell lines.
| Cells | HT29 | SW620 | Splenocyctes | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Time | 24 h | 48 h | 72 h | 24 h | 48 h | 72 h | 24 h | 48 h | 72 h |
| IC50 of DMCH (μM) | >30 | 9.800 ± 0.553 | 8.200 ± 0.761 | >30 | 7.500 ± 1.185 | 5.000 ± 0.157 | >30 | >30 | >30 |
| IC50 of curcumin (μM) | >30 | 26.700 ± 1.527 | 20.660 ± 1.155 | >30 | 18.630 ± 0.321 | 15.660 ± 1.524 | >30 | >30 | >30 |
Notes: The IC50 values of DMCH and curcumin in SW620 and HT29 after 24 h, 48 h, and 72 h of treatment. The IC50 value for splenocytes after 24 h, 48 h, and 72 h of treatment. All experiments were performed in triplicate. All treatments are expressed as mean ± standard error mean (S.E.M.).