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ICAM-1 mediated cell-cell interaction. The process of ICAM-1-mediated leukocyte migration and adhesion are essential for cell communication and connection. In the process of leukocyte migration, LFA-1 is activated after chemokines bind to receptors on endothelial cells, as shown in the yellow part. Besides, ICAM-1 is also involved in the interaction between immune cells and is an important element of the body’s defense.
