| ARC | Arcuate nucleus of the hypothalamus |
| BAMs | Border-associated macrophages |
| BBB | Blood–brain barrier |
| BMDC | Bone-marrow-derived cells |
| CAMs | CNS-associated macrophages |
| CCL2 | Chemokine C-C motif ligand-2 |
| CCR2 | C-C chemokine receptor type 2 |
| CD11b | Cluster of differentiation molecule 11B |
| CD169 | Sialoadhesin |
| CNS | Central nervous system |
| CSF1R | Colony stimulating factor 1 receptor |
| CX3CR1 | CX3C chemokine receptor 1 |
| CyTOF | Mass cytometry |
| DAM | Disease-associated microglia |
| DIO | Diet-induced obesity |
| DM | Dark microglia |
| EAE | Experimental autoimmune encephalomyelitis |
| FACS | Fluorescence-activated cell sorting |
| FFAs | Free fatty acids |
| GFAP | Glial fibrillary acidic protein |
| Hexb | Beta-hexosaminidase subunit beta |
| HFD | High-fat diet |
| IBA1 | Ionized calcium binding adaptor molecule 1 |
| iNOS | Inducible nitric oxide synthase |
| ITGAM | Integrin subunit alpha M |
| LHA | Lateral hypothalamic area |
| LPS | Lipopolysaccharide |
| MACS | Magnetic-activated cell sorting |
| MCP-1 | Monocyte chemoattractant protein-1 |
| ME | Median eminence |
| P2ry12 | Purinergic receptor P2Y12 |
| PVH | Paraventricular nucleus of the hypothalamus |
| PVMs | Perivascular macrophages |
| ROS | Reactive oxygen species |
| scRNA-seq | Single-cell RNA sequencing |
| SFAs | Saturated fatty acids |
| Siglec | Sialic acid-binding immunoglobulin super-family lectin |
| snRNA-seq | Single-nucleus RNA sequencing |
| TGF-β | Transforming growth factor beta |
| TLR4 | Toll-like receptor 4 |
| Tmem119 | Transmembrane protein 119 |
| TREM2 | Triggering receptor expressed on myeloid cells-2 |
| VEGF | Vascular endothelial growth factor |
| VMH | Ventromedial nucleus of the hypothalamus |