Table 4.

Examples of lncRNAs implicated in glucose metabolism alteration in breast cancer.

lncRNA	Deregulation	Functions and Targets	Reference
BCAR4	Upregulated in triple negative breast cancer	Interacts with GLI2; upregulates HK2 and PFKFB3; increases glucose uptake and lactate production	[88]
YIYA	Upregulated in breast cancer	Interacts with CDK6; increases phosphorylation PFKFB3; catalysis of glucose 6-phosphate to fructose bisphosphate	[86]
LINC00346	Upregulated in breast cancer cells	Sponges miR-148a/b; enhances GLUT-1 expression	[89]