Table 1.
Characteristics of eligible studies included in the systematic review.
| Author and Year | Region | Design | Recruitment Period | No. pts | Operation Modality | Reported Outcomes | NOS | Funding Source |
|---|---|---|---|---|---|---|---|---|
| Nasselli A 2008 | Italy | R cohort | 2002–2007 | 318 | ORP | BCR | 6 | NR |
| Vesely S 2014 | Czech | R case-control | 2001–2012 | 116 | ORP or LRP | BCR | 5 | NR |
| Bianchi L 2015 | Italy | R cohort | 1998–2013 | 319 | NR | Disease recurrence, CSM | 7 | None |
| Fossati N 2017 | EU | R cohort | 1996–2009 | 925 | NR | Disease recurrence | 7 | None |
| Roy S 2018 | Canada | R cohort e | 2005–2014 | 167 | NR | Disease recurrence | 6 | Sanofi and Bayer Health Care Pharmaceuticals |
| Spratt DE 2018 | US | R cohort | 1990–2015 | 477 | NR | Disease recurrence | 6 | GenomeDx Biosciences |
| Kim JK 2019 | Korea | R cohort | 2002–2014 | 96 | ORP or RARP | Disease recurrence | 6 | The National Research Foundation of Korea |
| Preisser F 2019 | Germany | R cohort | 1992–2016 | 11,604 | ORP or RARP | Disease recurrence, CSM, OM | 7 | None |
| Venclovas Z 2019 | Lithuania | R case-control | 2001–2017 | 433 | ORP | Disease recurrence, CSM | 5 | NR |
BCR: biochemical recurrence, CSM: cancer-specific free mortality, LRP: laparoscopic radical prostatectomy, NOS: The Newcastle-Ottawa Scale, NR: not reported, ORP: open radical prostatectomy, OM: overall mortality, R: retrospective, RARP: robot-assisted radical prostatectomy, US: United States.