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. 2021 Feb 25;22(5):2308. doi: 10.3390/ijms22052308

Figure 1.

Figure 1

Human super-family 2 DNA helicases containing a Fe-S cluster. A schematic representation of the DNA helicase polypeptide chain is reported. Color code is as follows: black, conserved helicase motifs (Q motif, Q, and helicase boxes from I to VI); grey, Timeless-binding motif (T) [9], Fe-S cluster (Fe-S) and Arch domain (Arch) domain. The related rare hereditary diseases are indicated for each DNA helicase.