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Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
Annotation process. A pT3 adenocarcinoma of the sigmoid colon. The first annotation in yellow marks the certain tumor tissue; in red the surrounding tissue, probably with adenoma parts; in blue the healthy mucosa; and in black the deleted unmarked areas.