Figure 2.

Expression scatterplots of CDK4 correlations with CDK2 and CDK6 in multiple cancer types. CDK4 expression was positively correlated with expressions of CDK2 and CDK6 in liver cancer, lung cancer, prostate cancer, pancreatic cancer, melanoma, head and neck cancer, glioblastomas, breast cancer, and cervical cancer cohorts (r = 0.06~0.69). CDK4 was negatively correlated with CDK6 expression in prostate cancer (r = −0.5). The strength of correlations between the genes is reflected by the purity-adjusted partial spearman’s rho value and estimated statistical significance, where a value of r = 1 means a perfect positive correlation and a value of r = −1 means a perfect negative correlation.