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. 2021 Feb 25;13(5):956. doi: 10.3390/cancers13050956

Figure 2.

Figure 2

Dose-dependent responses with carboplatin treatment. (A) Effect of carboplatin on tumor proliferation and apoptosis. Tissue was treated with 0.2, 2 or 20 µM of carboplatin for 72 h after 24 h from the start of cultivation (n = 7 for CTR and 2 µM, n = 2 for 0.2 and 20 µM). Error bars represent SEM. (B) Individual response of #10 and #11 to carboplatin determined by tumor proliferation and apoptosis. Error bars represent SEM. (C) Representative images of #10 and #11. Tissue was stained with antibodies against Ki67 and cleaved-PARP. Bar = 100 μm. Blue = Hoechst, red = panCK, green = Ki67 in proliferation/cPARP in apoptosis. # p < 0.01 (One-way ANOVA).