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. 2021 Feb 25;13(5):956. doi: 10.3390/cancers13050956

Table 1.

Patient data and experimental tissue response.

# Age TNM (2017) Grade BRCA1/2 PS ICD-O-C Days in Culture Treatment
Period
Tissue
Response
CP Ola
1 83 pT3c pN1a M0 G3 n.d. - 57 ≤14 - - -
3 62 pT3c pN0 M0 G3 n.d. - 57 ≤14 - - -
6 60 pT3a pN1a M0 G3 BRCA2mut - 57 ≤14 - - -
10 79 pT3c pN1b M0 G3 n.d. + 57 ≤7 72 h/6 d R R
11 67 pT3c pN1b M0 G3 no mut. - 57 ≤7 72 h/6 d PR PR
12 64 pT3c pN1b M0 G3 no mut. - 57 4 72 h NR R
17 63 ypT3c ypN0 M0 G3 no mut. + 56 4 72 h PR R
19 59 ypT3c ypN1 M0 G3 no mut. + 56 4 72 h NR PR
20 53 pT3c pN0 M0 G3 no mut + 56 4 72 h NR PR
22 60 pT3c pN0 M0 G3 no mut. + 56 4 72 h NR NR

All patients were female. # = specimen number, PS = patient serum, 2% PS was added to the culture media. CP = carboplatin, Ola = olaparib, R = response, PR = partial response, NR = non-response, n.d. = no data, no mut. = no somatic mutation, mut = mutated.