Table 1.
# | Age | TNM (2017) | Grade | BRCA1/2 | PS | ICD-O-C | Days in Culture | Treatment Period |
Tissue Response |
|
---|---|---|---|---|---|---|---|---|---|---|
CP | Ola | |||||||||
1 | 83 | pT3c pN1a M0 | G3 | n.d. | - | 57 | ≤14 | - | - | - |
3 | 62 | pT3c pN0 M0 | G3 | n.d. | - | 57 | ≤14 | - | - | - |
6 | 60 | pT3a pN1a M0 | G3 | BRCA2mut | - | 57 | ≤14 | - | - | - |
10 | 79 | pT3c pN1b M0 | G3 | n.d. | + | 57 | ≤7 | 72 h/6 d | R | R |
11 | 67 | pT3c pN1b M0 | G3 | no mut. | - | 57 | ≤7 | 72 h/6 d | PR | PR |
12 | 64 | pT3c pN1b M0 | G3 | no mut. | - | 57 | 4 | 72 h | NR | R |
17 | 63 | ypT3c ypN0 M0 | G3 | no mut. | + | 56 | 4 | 72 h | PR | R |
19 | 59 | ypT3c ypN1 M0 | G3 | no mut. | + | 56 | 4 | 72 h | NR | PR |
20 | 53 | pT3c pN0 M0 | G3 | no mut | + | 56 | 4 | 72 h | NR | PR |
22 | 60 | pT3c pN0 M0 | G3 | no mut. | + | 56 | 4 | 72 h | NR | NR |
All patients were female. # = specimen number, PS = patient serum, 2% PS was added to the culture media. CP = carboplatin, Ola = olaparib, R = response, PR = partial response, NR = non-response, n.d. = no data, no mut. = no somatic mutation, mut = mutated.