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. 2021 Feb 26;22(5):2346. doi: 10.3390/ijms22052346

Figure 1.

Figure 1

An algorithmic flow chart of the bioinformatics model of human diseases on the basis of differentially expressed genes (of domestic versus wild animals) that are orthologs of human genes associated with reproductive potential changes. Legend: Δ, gene expression change: deficit (↓), excess (↑); ♂♀, reproductive potential change: worse (←), improved (→); NCA, nearest common ancestor; PADJ, significance (Fisher’s Z-test with those corrections on multiple comparisons, which are available within the RNA-Seq data, as published by their authors [26,28,29]).