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. 2021 Feb 26;22(5):2347. doi: 10.3390/ijms22052347

Figure 3.

Figure 3

Heatmap and bar chart of log2 fold gene expression changes for IL-6 (A) and IL-8 (B) in NP-derived disc cells infected with C. acnes. Heatmap values are individual changes (3 × biological replicates) from eight donor samples, while the bar charts represent average donor changes. Results with LPS-positive controls are also shown. Top bars represent the log2 fold-change scale * p < 0.05; ** p < 0.01; *** p < 0.001; **** p < 0.0001.