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. 2021 Feb 25;10(5):903. doi: 10.3390/jcm10050903

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Proposal for a multiparametric personalized hepatocellular carcinoma screening in patients with cACLD. HBV—hepatitis B virus; HCV—hepatitis C virus; ALD—alcoholic liver disease; aMAP—hepatocellular carcinoma risk score, as described by Fan R et al. [68]; LSM—liver stiffness measurement; US—ultrasonography; aMRI—abbreviated magnetic resonance imaging; MDCT—multidetector computed tomography; AFP—alpha-fetoprotein; CEUS—contrast-enhanced ultrasonography; ⸸ 20 ng/mL cut-off value to be used for patients with a prior history or ongoing treatment for chronic viral hepatitis or curative-intent treatment for hepatocellular carcinoma; * a liver lesion which is hypo enhanced in the venous and late phase.