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. 2021 Feb 25;22(5):2313. doi: 10.3390/ijms22052313

Figure 1.

Figure 1

(A) Number of observations linking upregulated and downregulated miRNAs to PE. A total of 15 different studies linked upregulation of miR-210 with the pathogenesis of PE, eight times in circulation and seven times in the placenta. (B) Number of observations linking upregulated and downregulated miRNAs to IUGR. Three different studies linked upregulation of miR-424 with the pathogenesis of IUGR, one time in circulation and two times in the placenta. Bars rising above zero x-axis reference line indicate upregulation, and bars hanging below zero x-axis reference line indicate downregulation. A complete list of miRNAs and the number of studies linking them to each disease is in Table S5. Let-7*: let-7a, let-7b, let-7c, let-7e, let-7f, let-7g or let-7i.