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. 2021 Feb 25;13(5):957. doi: 10.3390/cancers13050957

Figure 4.

Figure 4

B. bre JCM92 boosted PD-1 blockade efficacy. (A) Tumor growth curves after administering B. breve strains, with or without PD-1 blockade. Data are expressed as the means ± SEM. p-values were determined by two-way ANOVA using Tukey’s post-test. (B,C) Immune cell profiling of spleen tissue in mice treated with PD-1 blockade in combination with B. bre JCM92 (B) or B. bre Bb03 (C) using flow cytometry analysis. Data are expressed as the means ± SEM. p-values were determined by one-way ANOVA using Tukey’s post-test. For all graphs, * p < 0.05, ** p < 0.01, *** p < 0.001, and ns, not significant.