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. 2021 Feb 26;13(5):975. doi: 10.3390/cancers13050975

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Effects of BXDC knockdown on the cytotoxicity of various anti-cancer agents in bladder cancer cells. MTT assay in 5637-control-shRNA vs. 5637-BXDC2-shRNA sublines (A) or UMUC3-control-shRNA vs. UMUC3-BXDC2-shRNA sublines (B) cultured for 72 h in the presence of MTX (0–2.0 µM), VBL (0–20 µM), DOX (0–2.0 µM), or GEM (0–20 µM). Cell viability is presented relative to that of each subline without anti-cancer drug treatment. Each value represents the mean (± SD) from at least 3 determinants.