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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Support Care Cancer. 2020 Sep 15;29(5):2509–2517. doi: 10.1007/s00520-020-05748-8

Table 2:

Factors associated with BRONJ

Variable Ref. OR for ONJ 95%CI p-value Risk rate of ONJ in the reference group Risk rate of ONJ in the exposure group
Calculus (n = 5837) None or mild 2.03 (1.08, 3.81) 0.028 0.67% 1.34%
Gingivitis (n = 5759) None or mild 2.11 (1.12, 3.98) 0.021 0.65% 1.37%
Periodontitis (n = 5516) < 4 mm 2.20 (1.18, 4.08) 0.013 0.59% 1.30%
Overall periodontal disease (n = 5636) None or mild 2.87 (1.49, 5.53) 0.002 0.61% 1.74%
Type of bisphosphonate (IB) ZA 0.61 (0.31, 1.21) 0.158 1.26% 0.77%
Type of bisphosphonate (CL) ZA 0.28 (0.13, 0.62) 0.002 1.26% 0.36%