TABLE 5.
Comparisons of baseline demographic and clinical characteristics between patients with stable and unstable subtypes in the Jankovic classification.
Variables | Stable (n = 49) (62.0%) | Unstable (n = 30) (38.0%) | p-value |
Age (years) | 61.3 ± 7.3 | 59.3 ± 7.2 | 0.230 |
Gender (male) | 22 (44.9%) | 17 (56.7%) | 0.310 |
Formal education (years) | 9.9 ± 3.4 | 9.1 ± 4.2 | 0.446 |
Age at onset (years) | 59.2 ± 7.4 | 57.2 ± 7.3 | 0.248 |
Duration of symptom onset (years) | 2.1 ± 1.5 | 2.0 ± 1.5 | 0.678 |
UPDRS part II | 8.8 ± 4.6 | 7.5 ± 4.2 | 0.169 |
UPDRS part III | 23.6 ± 11.5 | 21.1 ± 12.0 | 0.223 |
Modified H-Y stage | 1.6 ± 0.5 | 1.5 ± 0.5 | 0.321 |
MMSE | 27.0 ± 3.2 | 27.1 ± 2.8 | 0.627 |
MoCA | 22.6 ± 4.1 | 22.3 ± 3.9 | 0.715 |
HAMD | 9.7 ± 5.1 | 7.9 ± 5.2 | 0.137 |
HAMA | 7.0 ± 4.3 | 5.5 ± 3.8 | 0.154 |
PDSS | 119.8 ± 30.0 | 130.2 ± 17.6 | 0.108 |
NMSQuest | 9.2 ± 3.4 | 7.1 ± 3.5 | 0.008 |
Data are presented as the mean ± SD and n (%). Statistically significant (p < 0.05) values are indicated in bold. Univariate p-values were calculated using two-sample t-test, Mann–Whitney U-test, or Chi-squared test. UPDRS, unified Parkinson’s disease rating scale; H-Y, Hoehn and Yahr; MMSE, Mini-mental state examination; MoCA, Montreal Cognitive Assessment; HAMD, Hamilton Depression Scale; HAMA, Hamilton anxiety scale; PDSS, Parkinson disease sleep scale; NMSQuest, non-motor symptoms questionnaire.