FIGURE 8.

MSCs ameliorated hepatic cell death through inhibiting pyroptosis. The mRNA and protein levels of pyroptosis makers in HepG2 cells were measured after 24‐h treatment of PA (A, B). IL‐18 and IL‐1β in culture supernatant were measured by ELISA (C, D). The mRNA and proteins levels of pyroptosis markers in liver were detected in the three groups at the 24th week after HFD (E, F). Results are presented as means ± SD from three independent experiments, *P < .05 vs the control or BSA group; ^# P < .05 vs the PA or HFD group