FIGURE 3.

Analysis of cell communication in antral stage follicles. A, Circos plots show the top 20 highly expressed ligand‐receptor interactions in antral stage follicle. B. The expression of GDF9 (ligand)‐BMPR2 (receptor) gene pair. C, The expression of HDC (ligand)‐HRH2 (receptor) gene pair. D, The expression of GDF9 (ligand)‐FXYD6 (receptor) gene pair. E, The expression of RPS19 (ligand)‐C5AR1 (receptor) gene pair. F, The expression of TNFSF13 (ligand)‐TNFRSF1A (receptor) gene pair. G, Immunohistochemistry staining of HDC in primordial, secondary and antral stage oocytes. The scale bars represent 40 μm in low‐magnification view and 10 μm in high‐magnification view