FIGURE 1.

Scoparone inhibits Ang II infusion‐induced pathological cardiac hypertrophy in vivo. A, Heart weight /bodyweight ratio (HW/BW), heart weight/tibia length ratio (HW/TL) in mice from the four groups (n = 7 or 8 per group). B, Representative photographs of wheat germ agglutinin (WGA) stained sections and data of cardiomyocytes cross‐sectional area (CSA, n = 4).C, Echocardiographic parameters, including FS (fractional shortening), LVPWd (left ventricular posterior wall thickness end diastole), LVIDd (left ventricular internal diameter end diastole), LVIDs (left ventricular internal diameter end systole) and IVSd (interventricular septum thickness end diastole) were evaluated and calculated (n = 7 or 8). D, Real‐time PCR analysis of ANP (atrial natriuretic peptide), BNP (brain natriuretic peptide) and β‐myosin heavy chain (β‐MHC) mRNA level (n = 4).*P < 0.05 versus control group; ^# P < 0.05 versus Ang II group