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. Author manuscript; available in PMC: 2021 Mar 15.
Published in final edited form as: J Inherit Metab Dis. 2019 Oct 2;43(2):179–188. doi: 10.1002/jimd.12163

TABLE 3.

Inter-laboratory variation (expressed as CV%) with and without calibration using a DBS standard in 79 laboratories

Parameter Sample 1 Sample 2 Sample 3 Sample 4 Mean
Phenylalanine concentration (μmol/L) 120 330 420 940 452
Inter-laboratory CV without calibration 23% 20% 18% 20% 20%
Inter-laboratory CV with calibration 14% 9% 8% 9% 10%

Abbreviation: CV, coefficient of variation; DBS, dried blood spot.