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. 2021 Feb 22;13(2):632–640. doi: 10.1111/os.12891

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© 2021 The Authors. Orthopaedic Surgery published by Chinese Orthopaedic Association and John Wiley & Sons Australia, Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.

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Fig. 1 — Dose‐dependent effect of H₂O₂ and icariin on MC3T3‐E1 cells. (A) MC3T3‐E1 cell viability when treated with different concentrations of H₂O₂ (0.1 to 2 mM); (B) MC3T3‐E1 cell viability when cocultured with different doses of icariin (0.001 to 10 μM); (C) MC3T3‐E1 cell viability when cocultured with 0.2 mM H₂O₂ and 0.1 μM icariin from 0 to 48 h. *P < 0.05, compared with the control group.