Table 3.
Hemodynamic variables.
| Baseline | PC | Reperfusion | ||
|---|---|---|---|---|
| 30 | 60 | |||
| Heart Rate (bpm) | ||||
| Con | 318 ± 40 | 318 ± 51 | 338 ± 75 | 277 ± 62 |
| Man-PC | 293 ± 20 | 284 ± 22 | 273 ± 56 | 233 ± 60 |
| 5HD-PC+Man-PC | 300 ± 40 | 292 ± 35 | 291 ± 58 | 263 ± 69 |
| 5HD-PC | 314 ± 46 | 329 ± 52 | 275 ± 46 | 227 ± 57 |
| Man-PoC | 312 ± 38 | 306 ± 21 | 253 ± 51 | 266 ± 17 |
| 5HD-PoC+Man-PoC | 301 ± 49 | 289 ± 45 | 288 ± 63 | 270 ± 67 |
| 5HD-PoC | 297 ± 30 | 288 ± 18 | 286 ± 29 | 242 ± 37 |
| Left Ventricular-Developed Pressure (mmHg) | ||||
| Con | 118 ± 24 | 122 ± 22 | 12 ± 6 * | 24 ± 9 * |
| Man-PC | 114 ± 9 | 111 ± 23 | 21 ± 14 * | 33 ± 12 * |
| 5HD-PC+Man-PC | 112 ± 12 | 117 ± 9 | 21 ± 13 * | 29 ± 14 * |
| 5HD-PC | 114 ± 10 | 121 ± 16 | 14 ± 9 * | 22 ± 9 * |
| Man-PoC | 106 ± 11 | 119 ± 16 | 27 ± 14 * | 32 ± 10 * |
| 5HD-PoC+Man-PoC | 135 ± 15 | 145 ± 15 # | 18 ± 13 * | 25 ± 19 * |
| 5HD-PoC | 123 ± 21 | 133 ± 16 | 22 ± 13 * | 36 ± 14 * |
| Left Ventricular End Diastolic Pressure (mmHg) | ||||
| Con | 3 ± 2 | 4 ± 3 | 85 ± 23 * | 72 ± 21 * |
| Man-PC | 3 ± 1 | 3 ± 2 | 83 ± 16 * | 72 ± 14 * |
| 5HD-PC+Man-PC | 4 ± 2 | 4 ± 2 | 81 ± 14 * | 70 ± 12 * |
| 5HD-PC | 3 ± 1 | 4 ± 3 | 77 ± 20 * | 67 ± 20 * |
| Man-PoC | 3 ± 2 | 3 ± 2 | 75 ± 14 * | 65 ± 13 * |
| 5HD-PoC+Man-PoC | 5 ± 2 | 5 ± 2 | 109 ± 18 * | 97 ± 17 * |
| 5HD-PoC | 5 ± 2 | 5 ± 2 | 103 ± 10 * | 88 ± 7 * |
| Coronary Flow (mL/min) | ||||
| Con | 14 ± 2 | 14 ± 2 | 8 ± 1 * | 8 ± 2 * |
| Man-PC | 14 ± 2 | 14 ± 4 | 8 ± 1 * | 7 ± 1 * |
| 5HD-PC+Man-PC | 14 ± 3 | 15 ± 3 | 9 ± 3 * | 9 ± 3 * |
| 5HD-PC | 13 ± 2 | 15 ± 1 | 6 ± 2 * | 6 ± 2 * |
| Man-PoC | 14 ± 3 | 14 ± 3 | 8 ± 2 * | 7 ± 1 * |
| 5HD-PoC+Man-PoC | 14 ± 2 | 14 ± 2 | 7 ± 2 * | 7 ± 2 * |
| 5HD-PoC | 14 ± 3 | 13 ± 3 | 7 ± 2 * | 6 ± 2 * |
Data are mean ± SD. Con = Control; Man = Mannitol; 5HD = 5-hydroxydecanoate; PC = Preconditioning; PoC = Postconditioning. * p < 0.05 vs. Baseline; # p < 0.05 vs. Con.