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Development of nuclear counts in murine working and Purkinje myocytes. At the prenatal stage (ED14), all myocytes are mononucleated. Binucleation appears at P10. Summary analysis of nuclear counts from 3 adult (6 months of age) hearts (bottom row) shows that while the average proportion of the mononucleated working myocytes was 60%, all the analyzed Purkinje myocytes possessed only a single nucleus.
