Patterns of expression and distribution of CD200R in lung cancer. (A,B) Dynamic range charts that depict CD200R expression within the stromal compartment in NSCLC (A) and LCNEC (B) patients. Red lines represent the visual cutoffs that were used to define CD200R positive cases. (C–E) Different cores from the same representative NSCLC case, stained in YTMA423 blocks 1 (C), 2 (D) and 3 (E). (F–I) Scatter plots indicative of intratumoral heterogeneity of CD200R in NSCLC. Scatter plots of YTMA423 block 1 versus block 2 (F) and block 3 (G). Scatter plot between serial cuts of YTMA423 block 1 (H). Scatter plot between tumor and stromal expression of CD200R on the same cut (I). Abbreviations; DAPI, 4′,6-diamino-2-phenylindole; CK, Cytokeratin.