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. 2021 Feb 28;22(5):2440. doi: 10.3390/ijms22052440

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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The maturation state of oligodendrocytes is related to the myelin preservation in the optic nerve; (a–d): Graphs showing the different levels of precursor (PDGFRα⁺; a) and mature cells (CC1⁺ cells; d) between structures; (b,c): Graphs showing the correlation between the normalized MBP area and the percentage of PDGFRα⁺Olig2⁺ cells in both treatments and in the optic nerve (b) and spinal cord (c); (e,f): Graphs showing the results of Pearson´s correlation between the normalized MBP area and the CC1+ Olig2⁺ cells in both treatments and in the optic nerve (e) and spinal cord (f). EAE-VEH: n = 7; EAE-VP3.15: n = 10.