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. 2021 Feb 28;22(5):2429. doi: 10.3390/ijms22052429

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© 2021 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Levels of cytokines and adipokines in the rats’ spleen, median ± intervals of change: IL-1β (a) IL-6 (b) IL-10 (c) IL-17A (d) GM-CSF (e) TGF-1β (f) INF-γ (g). * the difference with the control group is significant; # the difference with the group receiving HFCD is significant, p < 0.05, Mann-Whitney test. The bracket above the bars denotes significant dependence on the factors: “diet” (D), “tyrosine” (Tyr), “tryptophan” (Trp), p < 0.05, 3-way ANOVA. The numbers of animals in the groups were 8.