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Correlation of SOCS3 and angiogenic genes’ expression levels with IDH mutation status. (A–C) Expression levels of corresponding genes in IDHs mutated (MT) and IDHs wildtype (WT) GBM. (D) Pearson correlation analysis of VEGFA and SOCS3 expression in primary glioma. (E) Heatmap analysis of SOCS3, TEK, and VEGFA genes’ methylation with IDH1 mutation status based on TCGA-LGG/GBM dataset. Gray area indicates cases with methylation data that are not available. ***: p < 0.001.
