Table 1.
Demographic, clinical and pathological characteristics of the total group of PTC patients and two subgroups according to BMI. Data are presented as the number of observations (percent) or mean ± SD.
| Parameters | Total | Group 1: BMI < 25 kg/m2 (n = 373) | Group 2: BMI ≥ 25 kg/m2 (n = 150) | p-Value |
|---|---|---|---|---|
| (n = 523) | ||||
| Sex: | 0.724 | |||
| Female | 456 (87.2) | 324 (86.9) | 132 (88.0) | |
| Male | 67 (12.8) | 49 (13.1) | 18 (12.0) | |
| Age at diagnosis (years) | 49.82 ± 15.67 | 48.59 ± 16.25 | 52.86 ± 13.73 | 0.005 * |
| Age: | 0.127 | |||
| <55 years | 306 (58.5) | 226 (60.6) | 80 (53.3) | |
| ≥55 years | 217 (41.5) | 147 (39.4) | 70 (46.7) | |
| TSH (mU/L) | 1.79 ± 1.14 | 1.45 ± 0.97 | 2.63 ± 1.08 | <0.0001 * |
| Glucose (mmol/L) | 4.86 ± 0.51 | 4.75 ± 0.49 | 5.16 ± 0.44 | <0.0001 * |
| Diagnosis of thyroid malignancy: | <0.0001 * | |||
| Before surgery | 317 (60.6) | 247 (66.4) | 70 (47.0) | |
| After surgery | 206 (39.4) | 125 (33.6) | 79 (53.0) | |
| Type of surgery: | <0.0001 * | |||
| Radical | 381 (72.8) | 291 (78.0) | 90 (60.0) | |
| Not radical | 142 (27.2) | 82 (22.0) | 60 (40.0) | |
| Reoperation needed: | 0.0001 * | |||
| No | 388 (74.2) | 294 (78.8) | 94 (62.7) | |
| Yes | 135 (25.8) | 79 (21.2) | 56 (37.3) | |
| pTNM stage: | 0.894 | |||
| I | 433 (82.8) | 307 (82.3) | 126 (84.0) | |
| II | 67 (12.8) | 50 (13.4) | 17 (11.3) | |
| III | 15 (2.9) | 10 (2.7) | 5 (3.3) | |
| IV | 8 (1.5) | 6 (1.6) | 2 (1.3) | |
| Tumor stage: | 0.012 * | |||
| pT1a | 209 (40.0) | 136 (36.5) | 73 (48.7) | |
| pT1b | 238 (45.5) | 181 (48.5) | 57 (38.0) | |
| pT2 | 61 (11.7) | 44 (11.8) | 17 (11.3) | |
| pT3 | 7 (1.3) | 7 (1.9) | 0 (0.0) | |
| pT4a | 3 (0.6) | 3 (0.8) | 0 (0.0) | |
| pT4b | 5 (0.9) | 2 (0.5) | 3 (2.0) | |
| Tumor size: | <0.0001 * | |||
| <5 mm | 89 (17.0) | 66 (17.7) | 24 (16.0) | |
| 5–10 mm | 120 (22.7) | 70 (18.7) | 49 (32.6) | |
| >10 mm | 314 (60.3) | 237 (63.6) | 77 (51.4) | |
| Lymph node metastasis: | 0.008 * | |||
| pN0 | 350 (66.9) | 266 (71.3) | 84 (56.0) | |
| pN1a | 145 (27.7) | 89 (23.9) | 56 (37.3) | |
| pN1b | 6 (1.1) | 3 (0.8) | 3 (2.0) | |
| pNx | 22 (4.2) | 15 (4.0) | 7 (4.7) | |
| Distant metastasis: | <0.0001 * | |||
| pM0 | 450 (86.0) | 337 (90.4) | 113 (75.3) | |
| pM1 | 19 (3.6) | 15 (4.0) | 4 (2.7) | |
| pMx | 54 (10.4) | 21 (5.6) | 33 (22.0) |
* statistically significant.