Table 3.

Univariable and multivariable logistic regression analysis of BMI ≥ 25 as a risk factor for disease severity indicators in PTC patients. The multivariable logistic regression model was adjusted for age, serum TSH level and serum glucose concentration.

PTC Severity Indicators	Univariable Logistic Regression Model			Multivariable Logistic Regression Model
	OR	±95% CI	p-Value	OR	±95% CI	p-Value
Advanced pTNM stage (III + IV)	1.09	0.43–2.72	0.849	-	-	-
pT progression (3 + 4)	0.61	0.17–2.21	0.452	-	-	-
Lymph node metastasis (pN1)	2.03	1.34–3.05	<0.001 *	1.41	0.86–2.31	0.168
Distant metastasis (pM1)	0.79	0.25–2.45	0.689	-	-	-
Bilaterality	52.85	16.05–173.90	<0.0001 *	22.76	6.39–81.08	<0.0001 *
Multifocality	30.90	18.0–52.9	<0.0001 *	20.07	9.54–42.24	<0.0001 *
Microcalcifications	2.56	1.69–3.87	<0.0001 *	1.65	0.99–2.75	0.051
Hypoechogenicity	1.77	1.04–3.02	0.034 *	1.46	0.79–2.71	0.224
High vascularity	2.73	1.82–4.08	<0.0001 *	1.9	1.20–3.03	0.006 *
Capsular invasion	1.49	1.00–2.20	0.045 *	1.07	0.67–1.72	0.768
Vascular invasion	1.47	0.99–2.17	0.052	1.06	0.66–1.71	0.795
Extrathyroidal extension	4.04	2.69–6.07	<0.0001 *	2.34	1.45–3.76	<0.001 *
Irregular tumor shape	2.64	1.77–3.95	<0.0001 *	1.87	1.18–2.97	0.007 *
Sharp margins	0.34	0.22–0.50	<0.0001 *	0.47	0.29–0.75	0.002 *

* statistically significant.