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PFKFB3 expression in human colon and rectal cancer. (A,B) PFKFB3 mRNA expression on colonic and rectal normal mucosa versus colonic and rectal tumors. (C,D) Kaplan–Meier plots for colon cancer overall survival (patients n = 475), and rectal cancer disease-free survival (patients n = 207), respectively, **** p < 0.0001.
