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. Author manuscript; available in PMC: 2021 Mar 15.
Published in final edited form as: J Hepatol. 2020 May 4;73(4):771–782. doi: 10.1016/j.jhep.2020.04.031

Fig. 7. Expression of human IRGC and IRGM genes.

Fig. 7.

(A) Cluster of immunity-related GTPases on mouse chromosome 18 and human chromosome 5. (B) Expression of IRGC and IRGM in liver biopsies of lean controls (Control, n = 7) and humans with non-alcoholic fatty liver disease (NAFLD, n = 11). Data were normalized to HPRT, analyzed by unpaired t test and presented as mean ± SD. *p <0.05. (C) Co-immunoprecipitation of co-transfected McArdle hepatocytes. (D) Scheme of the hypothesis how the interaction of the proteins IFGGA2, LC3B and ATGL promotes lipophagy. NAFLD, non-alcoholic fatty liver disease.