Subgroup analyses: risk of major adverse cardiovascular events among users vs. non-users of GLP-1 receptor agonist by age, sex, ST-segment elevation myocardial infarction (STEMI), and estimated glomerular filtration rate category. CI, confidence interval; eGFR, estimated glomerular filtration rate; HR, hazard ratio; P-value int., P-value of interaction; STEMI, ST-segment elevation myocardial infarction. Model adjusted for (when relevant): age, sex, smoking, body mass index, estimated glomerular filtration rate category, comorbidities (heart failure, cancer, hypertension, percutaneous coronary intervention, coronary artery bypass grafting, stroke, peripheral vascular disease, atrial fibrillation, Killip, ST-segment elevation myocardial infarction), and cardiovascular medications (aspirin, statins, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, beta-blockers, P2Y12 inhibitors).